Description

3-Chloro-4-Iodobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and a trifluoromethyl group on a benzene ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection chemicals, herbicides, and pesticides.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Sonogashira, and Heck couplings, enabling the introduction of complex aromatic systems.
• Chemical Biology & Proteomics: Utilized as a reagent for labeling and modifying biomolecules in research applications.
• Organic Synthesis: A versatile starting material for synthesizing a wide range of fluorinated and halogenated aromatic compounds for further chemical exploration.

Basic Information

Product Name	3-Chloro-4-Iodobenzotrifluoride
CAS No.	141738-80-9
Molecular Formula	C7H3ClF3I
Molecular Weight	305.45 g/mol
Synonyms	1-Chloro-2-iodo-5-(trifluoromethyl)benzene; 3-Chloro-4-iodobenzotrifluoride; 3-Chloro-4-iodo-alpha,alpha,α-trifluorotoluene; 3-Chloro-4-iodo(trifluoromethyl)benzene; 3-Chloro-4-iodobenzene, trifluoromethyl-; 4-Iodo-3-chlorobenzotrifluoride; 2-Iodo-5-chlorobenzotrifluoride; Benzene, 1-chloro-2-iodo-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Iodobenzotrifluoride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.