Description

2-Acetyl-Butanoic-D5 Acid Ethyl Ester is a high-purity, deuterium-labeled derivative of 2-acetylbutanoic acid ethyl ester, serving as a critical stable isotope-labeled internal standard. This compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry analyses, where it compensates for matrix effects and instrument variability. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, agrochemical, and environmental testing sectors for method development and regulatory compliance.

Application

• Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for precise quantification.
• Critical for metabolomics and pharmacokinetic studies in pharmaceutical R&D to track drug metabolites.
• Enables accurate residue analysis in environmental monitoring and food safety testing.
• Supports forensic and toxicological analysis by providing a reference for substance identification and quantification.
• Facilitates deuterium-labeling studies in organic chemistry and reaction mechanism elucidation.
• Applied in the synthesis of more complex deuterated compounds for specialized research applications.

Basic Information

Product Name	2-Acetyl-Butanoic-D5 Acid Ethyl Ester
CAS No.	141327-44-8
Molecular Formula	C8H7D5O3
Molecular Weight	159.21 g/mol (for deuterated form)
Synonyms	Ethyl 2-acetylbutanoate-d5; Ethyl 2-acetylbutyrate-d5; Ethyl 3-oxopentanoate-d5; 3-Oxopentanoic-d5 acid ethyl ester; Deuterated Ethyl 2-Acetylbutyrate; Ethyl 3-oxovalerate-d5; [2H5]-Ethyl 2-acetylbutanoate; Ethyl ester of 2-acetylbutanoic-d5 acid
EINECS	Contact for details

Quality Control

Our 2-Acetyl-Butanoic-D5 Acid Ethyl Ester is manufactured under strict quality systems to ensure exceptional isotopic purity and chemical integrity, which is paramount for analytical reference standards. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, GC-MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity, and analytical results is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.