Description

D-(+)-Methyl-α-(2-Thienylethamino)(2-Chlorophenyl)Acetate Hydrochloride is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its value lies in its role as a critical building block for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules.
• API Development: Used in research and development for constructing the core scaffold of potential new active pharmaceutical ingredients.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in stereoselective chemical reactions.
• Preclinical & Clinical Trial Material: Sourced for the production of compounds required for pharmacological studies and early-stage clinical batches.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing of pharmaceutical compounds.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	D-(+)-Methyl-α-(2-Thienylethamino)(2-Chlorophenyl)Acetate Hydrochloride
CAS No.	141109-19-5
Molecular Formula	C16H19Cl2NO2S
Molecular Weight	360.30 g/mol
Synonyms	Methyl (2R)-2-[(2-thienylmethyl)amino]-2-(2-chlorophenyl)acetate hydrochloride; (R)-Methyl 2-((thiophen-2-ylmethyl)amino)-2-(2-chlorophenyl)acetate hydrochloride; D-Methyl 2-[(2-thienylmethyl)amino]-2-(2-chlorophenyl)acetate HCl; (2R)-2-[(Thiophen-2-ylmethyl)amino]-2-(2-chlorophenyl)acetic acid methyl ester hydrochloride; 141109-19-5; UNII-4Q4H9L9B3Y
EINECS	Contact for details

Quality Control

Our D-(+)-Methyl-α-(2-Thienylethamino)(2-Chlorophenyl)Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under dry conditions to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.