Description

3-(4-Fluorophenyl)Thiophenol is a specialized aromatic thiol compound featuring a fluorinated phenyl group, making it a valuable building block in advanced organic synthesis. Its unique structure provides a reactive thiol (-SH) group and a fluorinated aromatic ring, enabling precise molecular modifications. This intermediate is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a versatile ligand for metal catalysts in cross-coupling reactions and other transition metal-catalyzed processes.
• Material Science: Employed in the creation of functional polymers, liquid crystals, and organic electronic materials due to its conjugated system.
• Chemical Research: A valuable reagent for academic and industrial R&D in organic chemistry, medicinal chemistry, and fluorochemistry.

Basic Information

Product Name	3-(4-Fluorophenyl)Thiophenol
CAS No.	141106-53-8
Molecular Formula	C12H9FS
Molecular Weight	204.26 g/mol
Synonyms	4-Fluorophenyl-3-thiophenol; (4-Fluorophenyl)thiophenol; 3-(p-Fluorophenyl)benzenethiol; 1-Fluoro-4-(3-mercaptophenyl)benzene; 3-Mercapto-4'-fluorobiphenyl; 4'-Fluoro-[1,1'-biphenyl]-3-thiol; 3-(4-Fluorophenyl)benzenethiol
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Thiophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its properties of being easily oxidized (store under inert atmosphere) and light-sensitive, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to air and light during use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.