Description

Br-Peg9-Ch2Ch2Br is a bifunctional polyethylene glycol (PEG) derivative featuring bromine termini, specifically designed as a versatile heterobifunctional linker. This compound matters for its ability to introduce PEG spacers and reactive sites for conjugation, enhancing solubility and biocompatibility in advanced material synthesis. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries for developing drug delivery systems, hydrogels, and functionalized surfaces.

Application

• Pharmaceutical Intermediates: Serves as a key building block for synthesizing antibody-drug conjugates (ADCs) and PEGylated therapeutics.
• Polymer Chemistry: Acts as an initiator or chain transfer agent in controlled radical polymerization (e.g., ATRP) to create functional polymers.
• Bioconjugation & Crosslinking: Used to link biomolecules (peptides, proteins) to surfaces, particles, or other molecules via nucleophilic substitution reactions.
• Material Science: Employed in the fabrication of hydrogels, functional coatings, and smart materials requiring hydrophilic PEG spacers.
• Nanoparticle Functionalization: Facilitates the surface modification of nanoparticles (e.g., gold, silica) to improve stability and introduce further chemical handles.
• Diagnostic Reagents: Utilized in the development of diagnostic assays and imaging probes where controlled spacing is critical.

Basic Information

Product Name	Br-Peg9-Ch2Ch2Br
CAS No.	140714-66-5
Molecular Formula	C₂₀H₄₀Br₂O₉
Molecular Weight	608.34 g/mol
Synonyms	1,11-Dibromo-3,6,9-trioxaundecane; α,ω-Dibromo-poly(ethylene glycol) (n≈9); Bis(2-bromoethyl) ether of triethylene glycol (extended); PEG9 dibromide; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(2-bromoacetate) (related structure); Heterobifunctional PEG bromide; Br-PEG9-Br; Dibromo-PEG9
EINECS	Contact for details

Quality Control

Our Br-Peg9-Ch2Ch2Br is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure compliance with research and cGMP-grade standards where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere after each use and desiccated for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Molecular Weight (GPC)	580 - 640 g/mol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.