Description

Acetamide, n-[2-(2-Iodo-5-Methoxy-1H-Indol-3-Yl)Ethyl]- is a specialized indole derivative and a high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex pharmacologically active molecules, particularly those targeting neurological and oncological pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical for lead optimization and the synthesis of novel drug candidates, where structural integrity and purity are paramount.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel serotonin receptor modulators and other neuroactive compounds.
• Medicinal Chemistry Research: Used in lead compound optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Biochemical Probe Development: Serves as a scaffold for creating labeled probes and tools for studying biological pathways and receptor binding.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a functionalized indole core with specific halogen and methoxy substituents.
• Academic & Contract Research: Utilized in university and CRO settings for investigating new chemical entities and reaction methodologies.

Basic Information

Product Name	Acetamide, n-[2-(2-Iodo-5-Methoxy-1H-Indol-3-Yl)Ethyl]-
CAS No.	140671-15-4
Molecular Formula	C₁₃H₁₅IN₂O₂
Molecular Weight	358.18 g/mol
Synonyms	N-[2-(2-Iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide; 2-Iodo-5-methoxy-N-[2-(1H-indol-3-yl)ethyl]acetamide; 140671-15-4; AI3-52342; AC1L4QZQ; AC1Q6S0L; SCHEMBL218064; CTK8G7125; MolPort-004-924-119
EINECS	Contact for details

Quality Control

Every batch of Acetamide, n-[2-(2-Iodo-5-Methoxy-1H-Indol-3-Yl)Ethyl]- is produced and tested under strict quality management systems to ensure it meets the exacting standards required for research and pharmaceutical development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.