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2-Amino-2-(4-Fluorophenyl)Ethanol CAS NO 140373-17-7
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CAS No.:140373-17-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Amino-2-(4-Fluorophenyl)Ethanol is a versatile chiral amino alcohol building block characterized by its fluorinated aromatic ring. This compound matters for its critical role as a key intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting central nervous system disorders. Pharmaceutical R&D departments and fine chemical manufacturers need this high-purity intermediate to develop new active pharmaceutical ingredients (APIs) and chiral catalysts.
Application
- Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel antidepressants, antipsychotics, and other CNS-active drugs.
- Asymmetric Catalyst Precursor: Used in the preparation of chiral ligands and organocatalysts for enantioselective synthesis.
- Agrochemical Research: Serves as a building block for developing new fluorinated pesticides and herbicides with enhanced activity.
- Material Science: Potential monomer or additive in the development of specialty polymers and advanced materials.
- Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
Basic Information
| Product Name | 2-Amino-2-(4-Fluorophenyl)Ethanol |
| CAS No. | 140373-17-7 |
| Molecular Formula | C8H10FNO |
| Molecular Weight | 155.17 g/mol |
| Synonyms | 2-Amino-2-(4-fluorophenyl)ethan-1-ol; (R/S)-2-Amino-2-(4-fluorophenyl)ethanol; 4-Fluoro-α-(aminomethyl)benzyl alcohol; 2-(4-Fluorophenyl)-2-aminoethanol; 1-(4-Fluorophenyl)-2-aminoethanol; 4-Fluorophenylethanolamine; Amino(4-fluorophenyl)methanol |
| EINECS | Contact for details |
Quality Control
Our 2-Amino-2-(4-Fluorophenyl)Ethanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and residual solvent screening to ensure it meets the high standards required for pharmaceutical development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity | Contact for details |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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