Description

Rac (2,3-Dimethoxyphenyl)-4-Piperidinemethanol is a chiral piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex heterocyclic structure.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study biological pathways and enzyme functions.
• Asymmetric Synthesis: The racemic mixture provides a starting point for chiral resolution studies or the development of enantioselective synthetic routes.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes from laboratory scale to pilot plant and commercial production.
• Academic & Institutional Research: Used in universities and research institutes for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Rac (2,3-Dimethoxyphenyl)-4-Piperidinemethanol
CAS No.	140235-25-2
Molecular Formula	C14H21NO3
Molecular Weight	251.32 g/mol
Synonyms	4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-, racemic; (±)-α-(2,3-Dimethoxyphenyl)-4-piperidinemethanol; rac-(2,3-Dimethoxyphenyl)(4-piperidinyl)methanol; 1-(2,3-Dimethoxybenzyl)piperidin-4-ol (tautomeric form); (RS)-(2,3-Dimethoxyphenyl)(piperidin-4-yl)methanol; 140235-25-2; (2,3-Dimethoxyphenyl)(4-piperidyl)methanol
EINECS	Contact for details

Quality Control

Our Rac (2,3-Dimethoxyphenyl)-4-Piperidinemethanol is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.