Description

3-Carboxy-5-Phosphono-1,2,3,4-Tetrahydroisoquinoline is a high-purity, multifunctional heterocyclic compound that serves as a critical building block and intermediate in advanced chemical synthesis. Its unique structure, featuring both carboxylic acid and phosphonic acid functional groups, makes it a versatile reagent for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine-tuning molecular interactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in developing advanced herbicides, pesticides, and plant growth regulators due to its bioactive phosphonate moiety.
• Ligand Synthesis: Serves as a chelating agent or ligand precursor in coordination chemistry and catalysis for industrial processes.
• Material Science: Incorporated into the design of functional polymers, metal-organic frameworks (MOFs), or surface modifiers.
• Bioconjugation Chemistry: Utilized for attaching molecules to biomolecules or surfaces in diagnostic and biotech applications.
• Chemical Biology Probe Development: Acts as a core structure for creating enzyme inhibitors or molecular probes to study biological systems.

Basic Information

Product Name	3-Carboxy-5-Phosphono-1,2,3,4-Tetrahydroisoquinoline
CAS No.	140202-46-6
Molecular Formula	C10H10NO5P
Molecular Weight	255.16 g/mol
Synonyms	5-Phosphono-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 1,2,3,4-Tetrahydro-5-phosphono-3-isoquinolinecarboxylic acid; 3-Carboxy-5-phosphono-1,2,3,4-tetrahydroisoquinoline; CPTHIQ; 140202-46-6; 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-5-phosphono-
EINECS	Contact for details

Quality Control

Our 3-Carboxy-5-Phosphono-1,2,3,4-Tetrahydroisoquinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.