Description

Formamide, n-[2-Hydroxy-5-[1-Hydroxy-2-[[2-(4-Methoxyphenyl)-1-Methylethyl]Amino]Ethyl]Phenyl]-, [S-(R*,R*)]-, (E)-2-Butenedioate (2:1) (Salt) is a high-purity, non-racemic salt form of a complex formamide derivative. This compound matters as a critical advanced pharmaceutical intermediate or reference standard for the development and production of specialized active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex, optically active drug molecules, particularly in the research phase.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Chemical Research: Serves as a specialized reagent in organic synthesis for constructing molecules with specific stereochemistry and functional groups.
• API Development: Integral in the process development and scale-up of new active pharmaceutical ingredients requiring high stereochemical purity.
• Life Science Research: Potential use as a biochemical tool or probe in exploratory pharmacological studies.

Basic Information

Product Name	Formamide, n-[2-Hydroxy-5-[1-Hydroxy-2-[[2-(4-Methoxyphenyl)-1-Methylethyl]Amino]Ethyl]Phenyl]-, [S-(R*,R*)]-, (E)-2-Butenedioate (2:1) (Salt)
CAS No.	140173-32-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Formoterol Fumarate EP Impurity C; (R,R)-Formoterol Fumarate Related Compound C; 1-(4-Methoxybenzyl)-2-[(4-{2-[(R)-2-Hydroxy-5-[(R)-1-hydroxy-2-(isopropylamino)ethyl]phenyl]formamido}butyl)amino]ethanol Fumarate Salt; N-[2-Hydroxy-5-[(1R)-1-Hydroxy-2-[[(1R)-2-(4-Methoxyphenyl)-1-Methylethyl]Amino]Ethyl]Phenyl]formamide (2E)-2-Butenedioate (2:1); Formamide, N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (2E)-2-butenedioate (2:1); Formoterol Related Compound C (Fumarate Salt); Arformoterol Fumarate Impurity C
EINECS	Contact for details

Quality Control

This high-purity compound is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.