Description

4-Thiazolidinecarboxylic Acid, 3-(Chlorocarbonyl)-, Methyl Ester, (S)- (9Ci) is a high-purity chiral building block and key synthetic intermediate. This compound matters for its role in constructing complex molecules, particularly in the synthesis of pharmaceuticals and bioactive compounds where stereochemical control is critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and antibiotic research.
• Peptidomimetic Chemistry: Used in the design and construction of peptidomimetics and constrained peptides to modulate biological activity and stability.
• Agrochemical Synthesis: Serves as a building block for developing advanced, stereospecific pesticides and herbicides.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Bioconjugation and Probe Synthesis: Utilized for creating labeled compounds and molecular probes for biochemical and diagnostic applications.
• Academic and R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	4-Thiazolidinecarboxylic Acid, 3-(Chlorocarbonyl)-, Methyl Ester, (S)- (9Ci)
CAS No.	139628-28-7
Molecular Formula	C6H8ClNO3S
Molecular Weight	209.65 g/mol
Synonyms	(S)-Methyl 3-(Chlorocarbonyl)-1,3-thiazolidine-4-carboxylate; (4S)-3-(Chlorocarbonyl)-1,3-thiazolidine-4-carboxylic Acid Methyl Ester; L-Thiazolidine-4-carboxylic Acid, 3-(chlorocarbonyl)-, Methyl Ester; Methyl (S)-3-(Chlorocarbonyl)thiazolidine-4-carboxylate; 139628-28-7; (S)-3-(Chlorocarbonyl)thiazolidine-4-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 4-Thiazolidinecarboxylic Acid, 3-(Chlorocarbonyl)-, Methyl Ester, (S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.