Description

Sodium Tris(1,1,1,3,3,3-Hexafluoroisopropoxy)Borohydride CAS NO 139494-68-1 is a highly specialized, fluorinated borohydride reagent known for its unique reactivity profile. This compound is valued for its powerful yet selective reducing capabilities, particularly in demanding synthetic environments where conventional hydride reagents are unsuitable. It is an essential tool for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the synthesis of complex fluorinated molecules and high-value intermediates.

Application

• Selective Reduction Agent in Pharmaceutical Synthesis: Used for the chemoselective reduction of specific functional groups (e.g., aldehydes, ketones) in the presence of other sensitive moieties during active pharmaceutical ingredient (API) development.
• Fluorinated Building Block Production: A key reagent for introducing or manipulating fluorinated segments in organic molecules, crucial for developing compounds with enhanced metabolic stability, bioavailability, and lipophilicity.
• Polymer and Material Science: Employed in the synthesis and modification of specialty polymers, coatings, and electronic materials where fluorinated components impart desired properties like chemical resistance, low surface energy, or thermal stability.
• Agrochemical Intermediate Synthesis: Facilitates the creation of novel fluorinated herbicides, insecticides, and fungicides by enabling precise reduction steps in complex synthetic pathways.
• Laboratory-Scale Research & Development: Serves as a critical reagent for methodological development and exploratory synthesis in academic and industrial R&D laboratories focusing on organofluorine chemistry.
• Catalyst and Ligand Preparation: Used in the preparation of sophisticated fluorinated ligands and catalyst precursors for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Sodium Tris(1,1,1,3,3,3-Hexafluoroisopropoxy)Borohydride
CAS No.	139494-68-1
Molecular Formula	C9H4BF18NaO3
Molecular Weight	508.10 g/mol
Synonyms	Sodium Tris(hexafluoroisopropyl)borohydride; Sodium Tris(1,1,1,3,3,3-hexafluoro-2-propoxy)borohydride; NaBH(OCH(CF3)2)3; Sodium Tris(hexafluoroisopropoxy)borohydride; Fluorinated Sodium Borohydride; STHB; Sodium Hydrotris(1,1,1,3,3,3-hexafluoroisopropoxy)borate(1-)
EINECS	Contact for details

Quality Control

Our Sodium Tris(1,1,1,3,3,3-Hexafluoroisopropoxy)Borohydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, which is critical for reproducible results in sensitive applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay purity, identity confirmation, and moisture content. Our quality management system is designed to meet the rigorous standards required for research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, containers must be carefully sealed immediately after use to exclude moisture and air. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (NMR/Titration)	≥ 95.0%
Moisture (KF)	≤ 1.0%
Solubility	Soluble in common organic solvents (e.g., THF, DME)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.