Description

(1R)-1-(2-Chlorophenyl)-2,2-Dimethylpropane-1,3-Diol CAS NO 139406-15-8 is a chiral diol building block of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functional group arrangement, making it a critical precursor for the development of enantiomerically pure pharmaceuticals and specialty chemicals. This compound is primarily needed by research institutions and industrial R&D departments focused on asymmetric synthesis, particularly in the pharmaceutical and agrochemical sectors.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) agents and other therapeutic compounds requiring high stereochemical purity.
• Agrochemical Research: Used in the development of novel, enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric hydrogenation, oxidation, and carbon-carbon bond-forming reactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances that demand precise molecular architecture.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with tailored physical properties.

Basic Information

Product Name	(1R)-1-(2-Chlorophenyl)-2,2-Dimethylpropane-1,3-Diol
CAS No.	139406-15-8
Molecular Formula	C12H17ClO2
Molecular Weight	228.72 g/mol
Synonyms	(1R)-1-(2-Chlorophenyl)-2,2-dimethyl-1,3-propanediol; (R)-1-(2-Chlorophenyl)-2,2-dimethylpropane-1,3-diol; (R)-2-Chlorophenyl Neopentyl Glycol; 1-(2-Chlorophenyl)-2,2-dimethylpropane-1,3-diol (R-enantiomer); Chiral 2-Chlorophenyl Diol; (R)-CPDiol; (1R)-CPD; (R)-1-(o-Chlorophenyl)-2,2-dimethyl-1,3-propanediol
EINECS	Contact for details

Quality Control

Our (1R)-1-(2-Chlorophenyl)-2,2-Dimethylpropane-1,3-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and development standards. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.