Description

5-(2-Thienylmethylene)-1,3-Thiazolidine-2,4-Dione is a specialized heterocyclic organic compound featuring a thiazolidinedione core fused with a thiophene moiety. This structure makes it a valuable key intermediate and pharmacological scaffold in advanced chemical synthesis. It is primarily sought by pharmaceutical R&D and fine chemical sectors for developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of thiazolidinedione-based drugs, which are explored for their potential in treating metabolic disorders.
• Organic Synthesis Reagent: Used in research and development for constructing complex heterocyclic molecules due to its reactive methylene group.
• Agrochemical Research: Serves as a precursor in developing new active ingredients for crop protection products.
• Material Science: Investigated as a monomer or additive for creating polymers with specific electronic or optical properties.
• Biochemical Research: Utilized in academic and industrial labs as a probe or inhibitor to study biological pathways involving similar structural motifs.

Basic Information

Product Name	5-(2-Thienylmethylene)-1,3-Thiazolidine-2,4-Dione
CAS No.	139336-31-5
Molecular Formula	C8H5NO2S2
Molecular Weight	211.26 g/mol
Synonyms	5-[(Thiophen-2-yl)methylene]-1,3-thiazolidine-2,4-dione; 5-(2-Thienylmethylene)-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[(2-thienyl)methylene]-; TZD derivative; Thiophene-thiazolidinedione hybrid; 139336-31-5; 5-(Thien-2-ylmethylene)thiazolidine-2,4-dione
EINECS	Contact for details

Quality Control

Our production of 5-(2-Thienylmethylene)-1,3-Thiazolidine-2,4-Dione adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.