Description

1,4-Dichlorobutane-2S-3S-Diol CAS NO 139165-54-1 is a high-purity chiral building block characterized by its specific stereochemistry and functional groups. This compound is valued for its role as a versatile intermediate in the synthesis of complex, optically active molecules, enabling precise control over the final product's properties. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing advanced active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where biological activity is highly dependent on molecular configuration.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and stereoselective synthesis within university and corporate research laboratories.

Basic Information

Product Name	1,4-Dichlorobutane-2S-3S-Diol
CAS No.	139165-54-1
Molecular Formula	C4H8Cl2O2
Molecular Weight	159.01 g/mol
Synonyms	(2S,3S)-1,4-Dichloro-2,3-butanediol; (2S,3S)-1,4-Dichlorobutane-2,3-diol; (2S,3S)-1,4-Dichloro-2,3-dihydroxybutane; (2S,3S)-1,4-DCB; (2S,3S)-1,4-Dichlorobutandiol; (2S,3S)-1,4-Dichloro-2,3-butylene glycol; (2S,3S)-1,4-Dichloro-2,3-butyleneglycol
EINECS	Contact for details

Quality Control

Our 1,4-Dichlorobutane-2S-3S-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.