Description

2,3-Dihydro-1H-Indol-2-Ylmethanol is a versatile heterocyclic building block and chiral intermediate of significant interest in advanced organic synthesis. Its core indoline structure with a hydroxymethyl substituent makes it a valuable precursor for constructing complex nitrogen-containing molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Serves as a building block for creating new pesticides, herbicides, and plant growth regulators with specific biological activity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the synthesis of dyes, pigments, and other performance chemicals requiring the indoline scaffold.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.

Basic Information

Product Name	2,3-Dihydro-1H-Indol-2-Ylmethanol
CAS No.	138969-57-0
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	2-(Hydroxymethyl)indoline; Indolin-2-ylmethanol; 2-Indolinemethanol; 1H-Indole-2-methanol, 2,3-dihydro-; (Indolin-2-yl)methanol; 2,3-Dihydro-1H-indole-2-methanol; 2-(Hydroxymethyl)-2,3-dihydro-1H-indole
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Indol-2-Ylmethanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.