Description

5-Chloro-1-(4-Fluoro-Phenyl)-3-Piperidin-4-Yl-1H-Indole is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective receptor ligands and enzyme inhibitors.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• CNS Drug Development: Used in the research and development of potential therapeutics targeting neurological and psychiatric disorders.
• Oncology Research: Employed as a building block for novel small-molecule candidates in anticancer drug discovery.
• Chemical Biology: Utilized as a probe or tool compound for studying biological pathways and target validation.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial APIs for clinical trials.

Basic Information

Product Name	5-Chloro-1-(4-Fluoro-Phenyl)-3-Piperidin-4-Yl-1H-Indole
CAS No.	138900-27-3
Molecular Formula	C19H18ClFN2
Molecular Weight	328.81 g/mol
Synonyms	5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole; 1H-Indole, 5-chloro-1-(4-fluorophenyl)-3-(4-piperidinyl)-; 4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidine; 138900-27-3; 5-Chloro-1-(4-fluoro-phenyl)-3-piperidin-4-yl-1H-indole; 3-(4-Piperidyl)-5-chloro-1-(4-fluorophenyl)indole
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-(4-Fluoro-Phenyl)-3-Piperidin-4-Yl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with complete chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.