Description

3-Acetyl-2-(Methylaminosulfonyl)Thiophene is a high-purity, functionalized thiophene derivative serving as a critical advanced intermediate in modern organic synthesis. This compound matters for its unique sulfonamide and acetyl functionalities, which enable precise molecular construction in complex chemical architectures. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science Precursor: Employed in the creation of functional polymers and organic electronic materials, such as conductive polymers and organic semiconductors.
• Chemical Synthesis Reagent: Acts as a versatile synthon for introducing the 2-(methylaminosulfonyl)thiophene moiety into more complex molecules via further derivatization.
• Academic & Contract Research: Serves as a valuable reagent for methodological studies in heterocyclic and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	3-Acetyl-2-(Methylaminosulfonyl)Thiophene
CAS No.	138891-01-7
Molecular Formula	C7H9NO3S2
Molecular Weight	219.28 g/mol
Synonyms	2-(N-Methylaminosulfonyl)-3-acetylthiophene; 3-Acetyl-2-[(methylamino)sulfonyl]thiophene; 1-[2-(Methylsulfamoyl)thiophen-3-yl]ethan-1-one; 3-Acetylthiophene-2-sulfonmethylamide; N-Methyl-3-acetylthiophene-2-sulfonamide; 3-Acetyl-2-methylaminosulfonylthiophene
EINECS	Contact for details

Quality Control

Every batch of 3-Acetyl-2-(Methylaminosulfonyl)Thiophene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.