Description

5-(tert-Butoxycarbonylamino)-1H-Indole-2-Carboxylic Acid is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Peptidomimetic Synthesis: Used to incorporate indole-based scaffolds into peptide analogs to enhance metabolic stability and binding affinity.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with indole core structures.
• Chemical Biology Probes: Utilized in the creation of fluorescent tags, enzyme inhibitors, and molecular probes for studying biological pathways.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential reagent in university laboratories and CROs (Contract Research Organizations) for methodological development and discovery chemistry.

Basic Information

Product Name	5-(tert-Butoxycarbonylamino)-1H-Indole-2-Carboxylic Acid
CAS No.	138730-81-1
Molecular Formula	C₁₄H₁₆N₂O₄
Molecular Weight	276.29 g/mol
Synonyms	5-((tert-Butoxycarbonyl)amino)-1H-indole-2-carboxylic acid; 5-(Boc-amino)indole-2-carboxylic acid; Boc-5-Aminoindole-2-carboxylic acid; 2-Carboxy-5-(tert-butoxycarbonylamino)indole; N-Boc-5-aminoindole-2-carboxylic acid; 5-[(2-Methylpropan-2-yl)oxycarbonylamino]-1H-indole-2-carboxylic acid; 138730-81-1; 5-(tert-Butoxycarbonylamino)indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(tert-Butoxycarbonylamino)-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements for GMP or advanced non-GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.