Description

5-(4-Fluorophenyl)Isoxazole is a high-purity fluorinated heterocyclic compound, identified by CAS No. 138716-37-7. This specialized chemical building block is valued for its unique structural motif, which is critical for imparting specific biological and physicochemical properties in advanced molecular design. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. Its role as a key intermediate enables the synthesis of novel active ingredients targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a core scaffold for developing next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Precursor: Used in the development of advanced organic materials, including liquid crystals and organic light-emitting diodes (OLEDs), where the isoxazole ring contributes to desired electronic properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	5-(4-Fluorophenyl)Isoxazole
CAS No.	138716-37-7
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	5-(4-Fluorophenyl)-1,2-oxazole; 4-Fluorophenyl Isoxazole; 5-(p-Fluorophenyl)isoxazole; 1,2-Oxazole, 5-(4-fluorophenyl)-; 138716-37-7; 5-(4-Fluorophenyl)-1,2-oxazole; 5-(4-Fluorophenyl)isoxazole
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)Isoxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.