Description

2,2,2-Trifluoro-1-(Pyridin-3-Yl)Ethanol is a versatile fluorinated pyridine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, combining a trifluoroethanol moiety with a pyridine ring, makes it highly valuable for introducing fluorine atoms and specific functional groups into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Building block for novel pesticides, herbicides, and fungicides where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Intermediate in the synthesis of advanced polymers, liquid crystals, and organic electronic materials that benefit from fluorine's properties.
• Fluorine Chemistry Studies: A valuable reference compound and starting material for academic and industrial research into new fluorination methodologies and reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke R&D projects and scale-up processes requiring high-purity, specialized fluorinated intermediates.

Basic Information

Product Name	2,2,2-Trifluoro-1-(Pyridin-3-Yl)Ethanol
CAS No.	138624-99-4
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	3-(2,2,2-Trifluoro-1-hydroxyethyl)pyridine; 1-(3-Pyridinyl)-2,2,2-trifluoroethanol; α-(Trifluoromethyl)-3-pyridinemethanol; 2,2,2-Trifluoro-1-(3-pyridyl)ethanol; 3-(1-Hydroxy-2,2,2-trifluoroethyl)pyridine; 1-(Pyridin-3-yl)-2,2,2-trifluoroethan-1-ol; (RS)-2,2,2-Trifluoro-1-(pyridin-3-yl)ethanol
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(Pyridin-3-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.