Description

Tripterygone is a bioactive diterpenoid compound isolated from the traditional medicinal plant *Tripterygium wilfordii* (Thunder God Vine). This high-purity reference standard is essential for pharmaceutical research and development, particularly in the study of anti-inflammatory and immunosuppressive pathways. It serves as a critical analytical standard for quality control in the production of herbal extracts and as a key intermediate in the synthesis of novel therapeutic agents. Researchers and manufacturers in the pharmaceutical, nutraceutical, and academic sectors rely on it for its consistent quality and biological relevance.

Application

• Pharmaceutical R&D as a reference standard for anti-inflammatory drug discovery.
• Active pharmaceutical ingredient (API) intermediate in the synthesis of specialized therapeutics.
• Quality control and standardization marker for Tripterygium wilfordii (Lei Gong Teng) herbal extracts and formulations.
• Biochemical research to study mechanisms of immunosuppression and autoimmune disease pathways.
• Pre-clinical studies investigating potential applications in oncology and rheumatology.
• Manufacturing of high-purity nutraceutical ingredients with standardized bioactive profiles.

Basic Information

Item	Detail
Product Name	Tripterygone
CAS No.	138570-50-0
Molecular Formula	C₂₀H₂₆O₆
Molecular Weight	362.42 g/mol
Synonyms	Triptogelin A; (1R,2S,5S,8S,9S,10R,11S,12S)-5,12-Dihydroxy-8-(hydroxymethyl)-1,2,6,6,9,11-hexamethyl-15-oxatetracyclo[8.5.0.0²,⁸.0¹¹,¹⁵]pentadec-13-en-14-one; Wilforlide A; Tripterygone A; Celastrol derivative; Thunder God Vine diterpenoid
EINECS	Contact for details

Quality Control

Our Tripterygone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurities is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The product is light-sensitive and should be handled under appropriate conditions to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.