Description

α-Methyl-4-[4-(Methoxymethyl)-2-Thiazolyl]Benzeneacetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial and research interest. This compound is a critical building block in the synthesis of advanced pharmaceutical agents, particularly those targeting inflammation and pain. It is essential for R&D laboratories, process development chemists, and manufacturers in the fine chemical and active pharmaceutical ingredient (API) sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel NSAID candidates and related therapeutic molecules.
• Chemical Research & Development: Used as a standard or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of final drug substances.
• Biochemical Research: Investigated for its biological activity and potential interactions with cyclooxygenase (COX) enzymes.

Basic Information

Product Name	α-Methyl-4-[4-(Methoxymethyl)-2-Thiazolyl]Benzeneacetic Acid
CAS No.	138568-66-8
Molecular Formula	C14H15NO3S
Molecular Weight	277.34 g/mol
Synonyms	2-(4-(4-(Methoxymethyl)thiazol-2-yl)phenyl)propanoic Acid; α-Methyl-4-(4-(methoxymethyl)-2-thiazolyl)benzeneacetic Acid; 4-[4-(Methoxymethyl)-2-thiazolyl]-α-methylbenzeneacetic Acid; Loxoprofen Intermediate; NSAID Intermediate; 2-[4-[4-(Methoxymethyl)-1,3-thiazol-2-yl]phenyl]propanoic Acid
EINECS	Contact for details

Quality Control

Our α-Methyl-4-[4-(Methoxymethyl)-2-Thiazolyl]Benzeneacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and production use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.