Description

3-Bromo-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate with significant synthetic utility. Its core value lies in its role as a key building block for the development of novel thiazole-containing pharmaceutical compounds, particularly COX-2 inhibitors. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, where it is used to create new therapeutic agents targeting inflammation and pain.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of novel NSAIDs and COX-2 inhibitors.
• Medicinal Chemistry Research: Key scaffold for structure-activity relationship (SAR) studies in anti-inflammatory drug discovery.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex, high-value organic molecules featuring the thiazole moiety.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Biochemical Research: Probe for studying enzyme pathways related to inflammation, such as cyclooxygenase (COX) enzymes.

Basic Information

Product Name	3-Bromo-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid
CAS No.	138568-62-4
Molecular Formula	C₁₂H₁₀BrNO₂S
Molecular Weight	312.18 g/mol
Synonyms	2-(3-Bromo-4-(thiazol-2-yl)phenyl)propanoic acid; α-Methyl-3-bromo-4-(2-thiazolyl)benzeneacetic acid; 3-Bromo-α-methyl-4-(2-thiazolyl)benzenacetic acid; 2-(3-Bromo-4-(1,3-thiazol-2-yl)phenyl)propanoic acid; 138568-62-4; Bromo-thiazolyl benzeneacetic acid derivative; NSAID intermediate 138568-62-4
EINECS	Contact for details

Quality Control

Our 3-Bromo-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.