Description

2-Amino-5-Methyl-3-Thiophenecarbonitrile is a versatile heterocyclic building block featuring both amino and nitrile functional groups on a thiophene core. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing functionalized thiophene scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a monomer or building block for developing conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Dye and Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.
• Ligand and Catalyst Development: The amino and nitrile groups make it a useful starting material for creating chelating ligands and organocatalysts.

Basic Information

Product Name	2-Amino-5-Methyl-3-Thiophenecarbonitrile
CAS No.	138564-58-6
Molecular Formula	C6H6N2S
Molecular Weight	138.19 g/mol
Synonyms	5-Methyl-2-amino-3-thiophenecarbonitrile; 3-Cyano-5-methyl-2-aminothiophene; 2-Amino-5-methylthiophene-3-carbonitrile; 5-Methyl-2-aminothiophene-3-carbonitrile; 2-Amino-3-cyano-5-methylthiophene; 5-Methyl-3-cyano-2-aminothiophene; 138564-58-6; 2-Amino-5-methyl-3-thiophenenitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Methyl-3-Thiophenecarbonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.