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3-((2-Aminoethyl)Carbamoyl)Psoralen CAS NO 138488-46-7
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CAS No.:138488-46-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-((2-Aminoethyl)Carbamoyl)Psoralen is a chemically modified psoralen derivative, a key intermediate in the development of advanced photoaffinity labeling probes and targeted photochemotherapeutic agents. Its core value lies in the functionalization of the psoralen scaffold with an aminoethylcarbamoyl group, which enhances its solubility and provides a versatile handle for bioconjugation. This compound is essential for researchers and manufacturers in pharmaceutical R&D, biochemistry, and molecular biology, particularly for studying nucleic acid-protein interactions and developing novel light-activated therapies.
Application
- Photoaffinity Labeling Probes: Acts as a critical intermediate for synthesizing probes to study biomolecular interactions and map binding sites.
- Photodynamic Therapy (PDT) Research: Serves as a building block for developing next-generation, targeted photosensitizers for cancer and dermatological treatments.
- Bioconjugation & Linker Chemistry: The primary amine group enables covalent attachment to antibodies, peptides, or other targeting molecules for creating drug conjugates.
- Nucleic Acid Cross-linking Studies: Used in biochemical research to investigate DNA and RNA structure, replication, and repair mechanisms.
- Chemical Biology Tool Development: Employed in creating activity-based probes for enzyme profiling and target identification.
- Academic & Industrial R&D: A valuable reagent for universities and biotech companies exploring novel applications of furocoumarin chemistry.
Basic Information
| Product Name | 3-((2-Aminoethyl)Carbamoyl)Psoralen |
| CAS No. | 138488-46-7 |
| Molecular Formula | C14H12N2O4 |
| Molecular Weight | 272.26 g/mol |
| Synonyms | 3-[(2-Aminoethyl)carbamoyl]psoralen; 3-(2-Aminoethylaminocarbonyl)psoralen; 3-Carbamoylethylpsoralen; Psoralen-3-carboxylic acid (2-aminoethyl)amide; 7H-Furo[3,2-g][1]benzopyran-7-one, 3-[(2-aminoethyl)carbamoyl]-; Aminoethylcarbamoyl Psoralen; AEC-Psoralen; Photoaffinity Labeling Psoralen Derivative |
| EINECS | Contact for details |
Quality Control
Our 3-((2-Aminoethyl)Carbamoyl)Psoralen is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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