Description

2-Thiopheneglyoxal Hydrate is a versatile heterocyclic building block and reactive aldehyde derivative. This compound matters as a key synthetic intermediate for constructing complex molecules, particularly in the development of pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and organic synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiophene or glyoxal-derived heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive aldehyde functionality.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of conductive polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags, molecular probes, and bioconjugation reagents.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-Thiopheneglyoxal Hydrate
CAS No.	138380-43-5
Molecular Formula	C6H6O3S
Molecular Weight	158.18 g/mol
Synonyms	2-Thienylglyoxal Hydrate; 2-Thenoylglyoxal Hydrate; 2-Thenoylformyl Hydrate; (2-Thienyl)-1,2-ethanedione Hydrate; 2-Thiopheneglyoxal Monohydrate; α-Oxo-2-thiopheneacetaldehyde Hydrate; Glyoxal, 2-thienyl-, hydrate (1:1); 2-Thienylglyoxal
EINECS	Contact for details

Quality Control

Our 2-Thiopheneglyoxal Hydrate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.