Description

1-Boc-7-Azaindole is a protected nitrogen heterocycle, specifically a Boc-protected derivative of 7-azaindole. This compound serves as a crucial advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients, particularly kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other targeted therapies.
• Organic Synthesis Reagent: Used as a protected precursor for introducing the 7-azaindole scaffold into complex molecules.
• Agrochemical Research: Intermediate in the development of new herbicides and fungicides.
• Material Science: Potential monomer or precursor for functional polymers and electronic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in CROs and CDMOs.

Basic Information

Product Name	1-Boc-7-Azaindole
CAS No.	138343-77-8
Molecular Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.25 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-1H-pyrrolo[2,3-b]pyridine; tert-Butyl 1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 1-Boc-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 1-[(1,1-dimethylethoxy)carbonyl]-; 1-N-Boc-7-azaindole; Boc-7-Azaindole; 7-Azaindole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-7-Azaindole is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.