Description

(1,3-Dioxo-Octahydro-Isoindol-2-Yl)-Acetic Acid CAS NO 138220-90-3 is a high-purity, functionalized isoindoline derivative serving as a versatile building block in advanced organic synthesis. Its value lies in its unique bicyclic lactam structure with an acetic acid side chain, making it an essential intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Peptidomimetics & Protease Inhibitors: Serves as a constrained scaffold in medicinal chemistry for creating peptide mimics and enzyme inhibitors.
• Polymer & Material Science: Functional monomer for synthesizing specialty polymers with tailored thermal or mechanical properties.
• Ligand & Catalyst Development: Precursor for chiral auxiliaries and ligands used in asymmetric catalysis.
• Chemical Research: A valuable reference standard and starting material in academic and industrial R&D for heterocyclic chemistry.

Basic Information

Product Name	(1,3-Dioxo-Octahydro-Isoindol-2-Yl)-Acetic Acid
CAS No.	138220-90-3
Molecular Formula	C10H13NO4
Molecular Weight	211.21 g/mol
Synonyms	2-(1,3-Dioxoisoindolin-2-yl)acetic acid (common name); 2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)acetic acid; 2-(1,3-Dioxoisoindolin-2-yl)ethanoic acid; Octahydroisoindole-1,3-dione-2-acetic acid; Isoindole-1,3(2H)-dione, 2-(carboxymethyl)hexahydro-; 138220-90-3; (Hexahydro-1,3-dioxoisoindol-2-yl)acetic acid
EINECS	Contact for details

Quality Control

Our (1,3-Dioxo-Octahydro-Isoindol-2-Yl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.