Description

(R)-(3-Hydroxy-2,3-Dimethylbutyl)Triphenylphosphonium Iodide is a high-value, chiral organophosphorus compound primarily used as a key intermediate in advanced organic synthesis. Its significance lies in its role as a versatile reagent for the stereoselective construction of complex molecules, particularly in the synthesis of chiral alcohols and other optically active targets. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, enantiomerically pure building blocks for their synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Synthesis: Employed in stereoselective reactions, such as Wittig-type olefinations, to introduce chiral centers with high enantiomeric excess.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, fragrances, and advanced materials where optical purity is critical.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure pesticides and herbicides.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis studies.
• Ligand Precursor: Can be utilized in the preparation of chiral phosphine ligands for transition metal catalysis.

Basic Information

Product Name	(R)-(3-Hydroxy-2,3-Dimethylbutyl)Triphenylphosphonium Iodide
CAS No.	138079-59-1
Molecular Formula	C24H28IO1P
Molecular Weight	490.35 g/mol
Synonyms	(R)-3-Hydroxy-2,3-dimethylbutyltriphenylphosphonium iodide; (R)-(3-Hydroxy-2,3-dimethylbutyl)triphenylphosphonium iodide; (R)-HDBTPI; (3R)-3-Hydroxy-2,3-dimethylbutyl-triphenylphosphonium iodide; Triphenyl[(3R)-3-hydroxy-2,3-dimethylbutyl]phosphonium iodide; (R)-Form of the phosphonium salt; Chiral hydroxyalkyltriphenylphosphonium salt
EINECS	Contact for details

Quality Control

Our (R)-(3-Hydroxy-2,3-Dimethylbutyl)Triphenylphosphonium Iodide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.