Description

5-Chloro-2H-Benzo[B][1,4]Oxazin-3(4H)-One is a versatile heterocyclic organic compound that serves as a critical synthetic intermediate and building block in advanced chemical synthesis. Its value lies in its unique benzoxazinone core, which is a privileged scaffold for developing molecules with targeted biological and material properties. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and microbial infections.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic systems and functionalized aromatic compounds in academic and industrial R&D.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials, dyes, and photoactive polymers.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control testing.

Basic Information

Product Name	5-Chloro-2H-Benzo[B][1,4]Oxazin-3(4H)-One
CAS No.	138035-68-4
Molecular Formula	C8H6ClNO2
Molecular Weight	183.59 g/mol
Synonyms	5-Chloro-3,4-dihydro-2H-1,4-benzoxazin-3-one; 5-Chloro-2H-1,4-benzoxazin-3(4H)-one; 5-Chloro-3,4-dihydro-1,4-benzoxazin-3-one; 5-Chloro-2H-benzo[b][1,4]oxazin-3(4H)-one; 138035-68-4; 5-Chloro-3-hydroxy-3,4-dihydro-2H-1,4-benzoxazine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2H-Benzo[B][1,4]Oxazin-3(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.