Description

2-(2-Aminopropyl)-5-Iodothiophene is a specialized halogenated thiophene derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a reactive amino group with an iodine substituent on a thiophene ring, enabling precise functionalization and cross-coupling reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the thiophene scaffold for bioactive molecule design.
• Material Science: Serves as a monomer or functional unit in the creation of conductive polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex heterocyclic systems.
• Ligand Preparation: Utilized for synthesizing specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Life Science Reagents: Employed in the preparation of fluorescent probes and biochemical tools for diagnostic applications.

Basic Information

Product Name	2-(2-Aminopropyl)-5-Iodothiophene
CAS No.	137945-32-5
Molecular Formula	C7H10INS
Molecular Weight	267.13 g/mol
Synonyms	5-Iodo-2-(2-aminopropyl)thiophene; 2-(2-Aminopropyl)-5-iodothiophene; 1-(5-Iodothiophen-2-yl)propan-2-amine; 5-Iodo-2-(2-aminopropyl)thiophene; 2-Aminopropyl-5-iodothiophene; 5-Iodo-2-(2-propylamine)thiophene; Thiophene, 5-iodo-2-(2-aminopropyl)-; 137945-32-5
EINECS	Contact for details

Quality Control

Our 2-(2-Aminopropyl)-5-Iodothiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are available upon request to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.