Description

2-Hydrazino-4-(trifluoromethyl)thiazole is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the reactive hydrazino group and the electron-withdrawing trifluoromethyl substituent, which enable the construction of complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those requiring the incorporation of the thiazole scaffold and fluorine atoms.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands, or organic electronic materials with unique properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein interactions.
• Heterocyclic Chemistry: A fundamental reagent for constructing complex fused-ring systems and other sophisticated thiazole derivatives in academic and industrial research.

Basic Information

Product Name	2-Hydrazino-4-(Trifluoromethyl)Thiazole
CAS No.	137929-07-8
Molecular Formula	C4H4F3N3S
Molecular Weight	183.16 g/mol
Synonyms	4-(Trifluoromethyl)-1,3-thiazol-2-ylhydrazine; 2-Hydrazinyl-4-(trifluoromethyl)-1,3-thiazole; 4-(Trifluoromethyl)-2-thiazolylhydrazine; 2-Hydrazino-4-trifluoromethylthiazole; 1,3-Thiazole, 2-hydrazinyl-4-(trifluoromethyl)-; 2-Hydrazino-4-(trifluoromethyl)-1,3-thiazole
EINECS	Contact for details

Quality Control

Our 2-Hydrazino-4-(trifluoromethyl)thiazole is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.