Description

(S)-2'-Amino-1,1'-Binaphthalen-2-Ol CAS NO 137848-29-4 is a high-purity, enantiomerically pure chiral binaphthol derivative, serving as a versatile and critical building block in asymmetric synthesis. Its value lies in its ability to act as a precursor for chiral ligands and organocatalysts, which are essential for controlling stereochemistry in pharmaceutical and fine chemical manufacturing. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic routes and high-value chiral intermediates.

Application

• Chiral Ligand Synthesis: A key precursor for constructing sophisticated axially chiral ligands used in asymmetric metal catalysis (e.g., for hydrogenation, coupling reactions).
• Organocatalyst Development: Serves as a core scaffold for creating novel organocatalysts that facilitate enantioselective transformations without metal ions.
• Pharmaceutical Intermediates: Employed in the research and production of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, infections, and other therapeutic areas.
• Agrochemical Research: Used in synthesizing chiral compounds for developing new, more effective, and selective pesticides and herbicides.
• Material Science: Investigated for the creation of chiral functional materials, including liquid crystals and molecular devices.
• Academic & Process Chemistry: A valuable tool for methodological studies in asymmetric synthesis and for scaling up chiral processes.

Basic Information

Product Name	(S)-2'-Amino-1,1'-Binaphthalen-2-Ol
CAS No.	137848-29-4
Molecular Formula	C₂₀H₁₅NO
Molecular Weight	285.34 g/mol
Synonyms	(S)-2-Amino-2'-hydroxy-1,1'-binaphthyl; (S)-2'-Amino-2-hydroxy-1,1'-binaphthyl; (S)-NOBIN; (S)-2-Amino-2'-hydroxy-1,1'-binaphthalene; (S)-1,1'-Bi-2-naphthol, 2'-amino-; (S)-2'-(Amino)-1,1'-binaphthalen-2-ol; (S)-2,2'-Dihydroxy-1,1'-binaphthyl-2'-amine; (S)-2'-Amino-[1,1'-binaphthalene]-2-ol
EINECS	Contact for details

Quality Control

Our (S)-2'-Amino-1,1'-Binaphthalen-2-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including HPLC for chemical purity and chiral purity (enantiomeric excess), alongside identity confirmation by spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.