Description

{3-Bromobicyclo[1.1.1]pentan-1-yl}methanol is a high-value, functionalized bicyclic building block with a unique strained hydrocarbon scaffold. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, agrochemical discovery, and the development of novel polymers or ligands.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders or requiring bioisosteric replacement of aromatic rings.
• Medicinal Chemistry Probe: Used to introduce the rigid, three-dimensional bicyclo[1.1.1]pentane (BCP) motif, a valuable scaffold for improving the physicochemical and pharmacokinetic properties of lead compounds.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides where the BCP core can enhance stability and biological activity.
• Material Science Building Block: Utilized in the creation of advanced polymers, cross-linkers, or ligands with unique steric and electronic properties.
• Chemical Biology Tool: Acts as a handle for bioconjugation or as a component in probe molecules for studying biological systems.
• Academic Research: A valuable reagent for methodological development in organic synthesis, particularly in cross-coupling and functionalization chemistry of strained systems.

Basic Information

Item	Details
Product Name	{3-Bromobicyclo[1.1.1]pentan-1-yl}methanol
CAS No.	137741-16-3
Molecular Formula	C6H9BrO
Molecular Weight	177.04 g/mol
Synonyms	(3-Bromobicyclo[1.1.1]pentan-1-yl)methanol; 3-Bromo-1-(hydroxymethyl)bicyclo[1.1.1]pentane; 1-(Hydroxymethyl)-3-bromobicyclo[1.1.1]pentane; BCP-Br-CH2OH; 3-Bromo-BCP-methanol; (3-Bromo-1-bicyclo[1.1.1]pentanyl)methanol
EINECS	Contact for details

Quality Control

Our {3-Bromobicyclo[1.1.1]pentan-1-yl}methanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Assay	Contact for details
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.