Description

(S)-3-Bromo-1,2-Propanediol CAS NO 137490-63-2 is a chiral building block of significant importance in asymmetric synthesis and pharmaceutical development. Its value lies in its utility as a versatile intermediate for constructing more complex, optically active molecules. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for advanced R&D and production.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of β-blockers, antiviral agents, and other therapeutic compounds.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where the specific stereochemistry can be critical for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis to induce high enantioselectivity in chemical reactions.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins where the bromo and hydroxyl functionalities allow for further modification and cross-linking.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating libraries of chiral compounds.
• Flavor and Fragrance Industry: Potential use as an intermediate in the synthesis of chiral aroma chemicals and flavoring agents.

Basic Information

Product Name	(S)-3-Bromo-1,2-Propanediol
CAS No.	137490-63-2
Molecular Formula	C3H7BrO2
Molecular Weight	154.99 g/mol
Synonyms	(S)-3-Bromopropane-1,2-diol; (S)-3-Bromo-1,2-dihydroxypropane; (S)-3-Bromoglycerol; (S)-1,2-Dihydroxy-3-bromopropane; (S)-β-Bromohydrin glycerol; (S)-3-Bromopropylene glycol; (S)-3-Bromo-1,2-propanediol; (S)-3-Bromopropanediol
EINECS	Contact for details

Quality Control

Our (S)-3-Bromo-1,2-Propanediol is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, identity confirmation by IR and NMR spectroscopy, and purity assessment. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.