Description

2-(tert-Butyldimethylsilyl)Thiazole is a high-value organosilicon-protected heterocyclic building block, essential for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise, stable intermediates for constructing complex molecules. It is primarily utilized in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key protected synthon in the synthesis of drug candidates, particularly those containing thiazole or modified nucleoside scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the thiazole moiety imparts biological activity.
• Organometallic Chemistry: Serves as a ligand precursor or a stabilizing group in the development of catalysts and metal-organic complexes.
• Material Science Research: Employed in the creation of novel organic semiconductors, liquid crystals, or polymers with specific electronic properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki or Stille couplings for carbon-carbon bond formation.
• Academic & R&D: A valuable reagent for methodological development and exploratory synthesis in university and corporate research laboratories.

Basic Information

Product Name	2-(tert-Butyldimethylsilyl)Thiazole
CAS No.	137382-38-8
Molecular Formula	C9H17NSSi
Molecular Weight	199.39 g/mol
Synonyms	2-[(1,1-Dimethylethyl)dimethylsilyl]thiazole; 2-(Tert-butyldimethylsilyl)thiazole; 2-(tert-Butyldimethylsilyl)-1,3-thiazole; TBDMS-Thiazole; Thiazole, 2-[(1,1-dimethylethyl)dimethylsilyl]-; 2-(tert-Butyldimethylsilanyl)thiazole
EINECS	Contact for details

Quality Control

Every batch of 2-(tert-Butyldimethylsilyl)Thiazole is produced under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee reliable and consistent performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.