Description

2-Indolizinecarboxylicacid,8-Aminooctahydro-3-Oxo-,[2S-(2Alpha,8Alpha,8Aalpha)]-(9Ci) is a high-purity, stereochemically defined indolizine derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated chiral building block, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Academic & Industrial Research: A valuable tool compound for methodological studies in organic chemistry, including new cyclization and functionalization reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	2-Indolizinecarboxylicacid,8-Aminooctahydro-3-Oxo-,[2S-(2Alpha,8Alpha,8Aalpha)]-(9Ci)
CAS No.	137038-27-8
Molecular Formula	C11H16N2O3
Molecular Weight	224.26 g/mol
Synonyms	(2S,8S,8aS)-8-Amino-3-oxooctahydro-2-indolizinecarboxylic acid; 8-Amino-3-oxooctahydroindolizine-2-carboxylic acid; (2S,8S,8aS)-8-Amino-3-oxo-1,2,3,5,6,7,8,8a-octahydroindolizine-2-carboxylic acid; 2-Carboxy-8-amino-3-oxooctahydroindolizine; (2S,8S,8aR)-8-Amino-3-oxooctahydroindolizine-2-carboxylic acid (enantiomer); 137038-27-8; 2-Indolizinecarboxylic acid, 8-aminooctahydro-3-oxo-, (2S,8S,8aS)-
EINECS	Contact for details

Quality Control

Our 2-Indolizinecarboxylicacid,8-Aminooctahydro-3-Oxo-,[2S-(2Alpha,8Alpha,8Aalpha)]-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) providing full chromatographic and spectroscopic data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.