Description

2-Indolizinecarboxylicacid,8-Aminooctahydro-3-Oxo-,[2R-(2Alpha,8Beta,8Abeta)]-(9Ci) is a complex, stereochemically defined indolizine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its unique fused bicyclic structure and functional groups, enabling the construction of sophisticated molecular architectures with high precision. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides that leverage its unique indolizine core for biological activity.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts for stereoselective transformations.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs to modulate pharmacokinetic and pharmacodynamic properties.
• Chemical Biology Probes: Utilized in the synthesis of specialized molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Institutional Research: A valuable compound for fundamental research in synthetic organic chemistry and heterocyclic chemistry at universities and R&D institutes.

Basic Information

Item	Detail
Product Name	2-Indolizinecarboxylicacid,8-Aminooctahydro-3-Oxo-,[2R-(2Alpha,8Beta,8Abeta)]-(9Ci)
CAS No.	137002-58-5
Molecular Formula	C11H16N2O3
Molecular Weight	224.26 g/mol
Synonyms	(2R,8R,8aR)-8-Amino-3-oxooctahydro-2-indolizinecarboxylic Acid; (2R,8R,8aR)-8-Amino-3-oxo-1,2,3,5,6,7,8,8a-octahydroindolizine-2-carboxylic Acid; 8-Amino-3-oxooctahydro-2-indolizinecarboxylic Acid, (2R,8R,8aR)-; 2-Indolizinecarboxylic acid, 8-aminooctahydro-3-oxo-, (2R,8R,8aR)-; (2R,8R,8aR)-8-Amino-3-oxo-octahydroindolizine-2-carboxylic Acid; 137002-58-5; (2R,8R,8aR)-8-Amino-3-oxo-1,2,3,5,6,7,8,8a-octahydroindolizine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a cGMP-compliant quality management system to ensure traceability and consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.