Description

5-Fluoro-6-Methoxy-1H-Indole-2-Carboxylic Acid is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the introduction of specific fluorinated and methoxylated indole scaffolds. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex molecules in material science and specialty chemistry applications.
• Biochemical Probe Development: Employed in research to create labeled compounds or probes for studying biological pathways and enzyme interactions.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs) focused on heterocyclic chemistry.

Basic Information

Product Name	5-Fluoro-6-Methoxy-1H-Indole-2-Carboxylic Acid
CAS No.	136818-65-0
Molecular Formula	C10H8FNO3
Molecular Weight	209.18 g/mol
Synonyms	5-Fluoro-6-methoxy-1H-indole-2-carboxylic acid; 5-Fluoro-6-methoxyindole-2-carboxylic acid; 2-Carboxy-5-fluoro-6-methoxyindole; 1H-Indole-2-carboxylic acid, 5-fluoro-6-methoxy-; 136818-65-0; 5-F-6-MeO-1H-Indole-2-COOH; 5-Fluoro-6-methoxy-2-indolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methoxy-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.