Description

Methyl 5-Fluoro-6-Methoxy-1H-Indole-2-Carboxylate is a high-purity, fluorinated indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its precise molecular architecture, which enables the construction of complex pharmacophores and functional materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: An essential reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Fluorine Chemistry: Utilized as a model compound for studying the effects of fluorine substitution on indole reactivity and biological activity.

Basic Information

Product Name	Methyl 5-Fluoro-6-Methoxy-1H-Indole-2-Carboxylate
CAS No.	136818-64-9
Molecular Formula	C11H10FNO3
Molecular Weight	223.20 g/mol
Synonyms	5-Fluoro-6-methoxy-1H-indole-2-carboxylic acid methyl ester; Methyl 5-fluoro-6-methoxyindole-2-carboxylate; 2-Carbomethoxy-5-fluoro-6-methoxyindole; 1H-Indole-2-carboxylic acid, 5-fluoro-6-methoxy-, methyl ester; 136818-64-9; 5-Fluoro-6-methoxyindole-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Fluoro-6-Methoxy-1H-Indole-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.