Description

6-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester is a high-purity fluorinated indole derivative, a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop novel fluorinated pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Material Science: Serves as a monomer or building block for specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or labeled compound in biochemical assays and diagnostic research.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	6-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester
CAS No.	136818-43-4
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	Methyl 6-Fluoro-1H-indole-2-carboxylate; 6-Fluoroindole-2-carboxylic Acid Methyl Ester; 2-Carbomethoxy-6-fluoroindole; 6-Fluoro-1H-indole-2-carboxylic acid, methyl ester; Methyl 6-fluoroindole-2-carboxylate; 136818-43-4; 6-Fluoro-2-indolecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1H-Indole-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.