Description

6-Acetylmorphine-D3 is a stable isotope-labeled internal standard, specifically a deuterated analog of 6-acetylmorphine, a key metabolite of heroin. This compound is essential for providing unmatched accuracy and reliability in quantitative mass spectrometry analysis. It is primarily required by forensic, clinical, and pharmaceutical research laboratories for precise drug testing, method development, and compliance with stringent regulatory standards.

Application

• Quantitative Internal Standard for LC-MS/MS: Used as a critical reference compound for the accurate quantification of 6-acetylmorphine and related opiates in biological matrices such as urine, blood, and hair.
• Forensic Toxicology: Essential for confirmatory drug testing in law enforcement and workplace drug screening programs to ensure reliable and legally defensible results.
• Clinical Research: Supports studies on drug metabolism, pharmacokinetics, and exposure assessment in controlled clinical trials.
• Method Development & Validation: Serves as a key component in developing, optimizing, and validating new analytical methods for opiate detection.
• Quality Control & Assurance: Employed in laboratory QC protocols to monitor assay performance, accuracy, and precision over time.
• Reference Material Production: Used in the preparation of certified reference materials (CRMs) and proficiency testing samples.

Basic Information

Item	Detail
Product Name	6-Acetylmorphine-D3
CAS No.	136765-25-8
Molecular Formula	C19H18D3NO4
Molecular Weight	330.39 g/mol
Synonyms	6-Monoacetylmorphine-D3; 6-MAM-D3; (5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol 6-acetate-D3; 6-Acetyl Morphine D3; Heroin Metabolite-D3; 6-AM-D3; Deuterated 6-Acetylmorphine; 6-Acetylmorphine (tri-deuterated)
EINECS	Contact for details

Quality Control

Our 6-Acetylmorphine-D3 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content. We adhere to relevant standards for reference materials to ensure reliable and reproducible performance in your critical assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.