Description

1,3-Dioxolane-4-Butanol, .Beta.-Methoxy-2,2-Dimethyl-.Alpha.-Pentyl-.Delta.-(Phenylmethoxy)-, 4R-4R*(.Alpha.R*,.Beta.R*,.Delta.S*)- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the production of complex, biologically active molecules, where its specific stereochemistry is essential for efficacy. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in the areas of antiviral and anticancer therapies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates, especially for antiviral and oncology applications.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with defined three-dimensional architecture, crucial for drug discovery.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Academic & Industrial Research: Used as a reference standard or starting material in methodological studies and the exploration of new chemical spaces.
• Fine Chemical Production: Acts as a precursor for other high-value, specialty chemicals requiring specific stereochemical features.

Basic Information

Product Name	1,3-Dioxolane-4-Butanol, .Beta.-Methoxy-2,2-Dimethyl-.Alpha.-Pentyl-.Delta.-(Phenylmethoxy)-, 4R-4R*(.Alpha.R*,.Beta.R*,.Delta.S*)-
CAS No.	136759-82-5
Molecular Formula	C19H30O5
Molecular Weight	338.44 g/mol
Synonyms	(4R,4aR,6R,8aS)-6-Methoxy-2,2,4a-trimethyl-4-[(phenylmethoxy)methyl]-4,4a,5,6,7,8,8a,9-octahydro-1,3-benzodioxin-8-ol; (4R,4aR,6R,8aS)-6-Methoxy-2,2,4a-trimethyl-4-[(phenylmethoxy)methyl]octahydro-1,3-benzodioxin-8-ol; β-Methoxy-2,2-dimethyl-α-pentyl-δ-(phenylmethoxy)-1,3-dioxolane-4-butanol (4R,4aR,6R,8aS)-; Chiral 1,3-dioxolane butanol derivative; Benzyl-protected chiral diol ether.
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Butanol derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.