Description

Trimethylsilyl 3-(3,4-Bis[(Trimethylsilyl)Oxy]Phenyl)-2-[(Trimethylsil Yl)Amino]Propanoate CAS NO 136655-95-3 is a highly functionalized, multi-silylated organic compound primarily used as a key synthetic intermediate and protecting group reagent. Its value lies in its ability to protect sensitive amine and phenol functionalities during complex multi-step organic syntheses, particularly for pharmaceutical actives. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable building blocks for sophisticated molecular construction.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of complex drug molecules, especially those containing catechol or amino acid derivatives.
• Protecting Group Reagent: Used to temporarily mask amine and phenolic hydroxyl groups during multi-step synthetic sequences to prevent unwanted side reactions.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Peptide & Protein Research: Employed in the modification and protection of amino acid side chains in peptide chemistry.
• Material Science Precursor: Serves as a starting material for creating functionalized siloxane polymers or surface-modifying agents.
• Analytical Derivatization: Used to derivative polar compounds for Gas Chromatography (GC) or Mass Spectrometry (MS) analysis to improve volatility and detection.

Basic Information

Item	Details
Product Name	Trimethylsilyl 3-(3,4-Bis[(Trimethylsilyl)Oxy]Phenyl)-2-[(Trimethylsil Yl)Amino]Propanoate
CAS No.	136655-95-3
Molecular Formula	C24H47NO5Si4
Molecular Weight	554.0 g/mol
Synonyms	3-(3,4-Bis(trimethylsiloxy)phenyl)-2-(trimethylsilylamino)propanoic acid trimethylsilyl ester; TMS-DOPA derivative; Tris(trimethylsilyl) 3,4-dihydroxyphenylalanine derivative; N,O,O-Tris(trimethylsilyl)-L-DOPA TMS ester; 2-[(Trimethylsilyl)amino]-3-[3,4-bis(trimethylsiloxy)phenyl]propanoic acid trimethylsilyl ester; Protected L-DOPA; Per-TMS-DOPA
EINECS	Contact for details

Quality Control

Every batch of our Trimethylsilyl 3-(3,4-Bis[(Trimethylsilyl)Oxy]Phenyl)-2-[(Trimethylsil Yl)Amino]Propanoate is produced and tested under strict quality management systems. We ensure compliance with relevant industry standards for high-purity synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.