Description

L-α-Dilauroyl Phosphatidylcholine-D46 is a deuterated phospholipid, specifically a phosphatidylcholine with two lauroyl chains where the hydrogen atoms are replaced by deuterium. This high-purity, isotopically labeled compound is critical for advanced research requiring precise molecular tracking and analysis. It is primarily utilized by scientists and formulators in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as metabolic studies, NMR spectroscopy, and the development of sophisticated lipid-based delivery systems.

Application

• Biophysical Research & NMR Spectroscopy: Acts as a stable isotopic tracer for detailed structural and dynamic studies of lipid membranes and protein-lipid interactions.
• Pharmaceutical R&D (Lipid Nanoparticles & Liposomes): Serves as a key deuterated excipient in the formulation and quality control of advanced drug delivery systems, including mRNA-LNPs.
• Metabolic Pathway Analysis: Used in mass spectrometry-based studies to trace phospholipid metabolism and turnover in biological systems.
• Reference Standard & Analytical Chemistry: Provides a high-purity internal standard for the accurate quantification of phosphatidylcholines in complex samples.
• Membrane Protein Studies: Facilitates the stabilization and structural analysis of membrane proteins in deuterated lipid environments.
• Advanced Material Science: Employed in the development of deuterated biomimetic surfaces and sensors.

Basic Information

Product Name	L-α-Dilauroyl Phosphatidylcholine-D46
CAS No.	136565-60-1
Molecular Formula	C34D46NO8P
Molecular Weight	~662.9 g/mol (deuterated form)
Synonyms	1,2-Dilauroyl-sn-glycero-3-phosphocholine-d46; DLPCD46; Deuterated DLPC; 1,2-Didodecanoyl-sn-glycero-3-phosphocholine-d46; PC(12:0/12:0)-d46; Phosphatidylcholine-d46 (12:0/12:0); Lauryl Phosphatidylcholine-d46; Isotopically Labeled Phospholipid
EINECS	Contact for details

Quality Control

Every batch of L-α-Dilauroyl Phosphatidylcholine-D46 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment. Our quality assurance protocol includes advanced techniques such as NMR, LC-MS, and HPLC to verify critical parameters. A comprehensive Certificate of Analysis (COA) detailing batch-specific results, including deuterium incorporation level, is provided with each shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR & MS)	Conforms to structure
Assay (HPLC)	≥ 98.0% (by area)
Deuterium Incorporation	≥ 98 atom % D
Solubility	Soluble in chloroform, ethanol; forms dispersions in water
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.