Description

1,1-Cyclopropane-2,2,3,3-D4-Dicarboxylic Acid is a high-purity, isotopically labeled derivative of cyclopropane-1,1-dicarboxylic acid, where four hydrogen atoms are replaced with deuterium (D). This compound is an essential building block and internal standard for advanced analytical and synthetic chemistry, offering unique value in research requiring precise molecular tracking. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications in drug metabolism studies, quantitative mass spectrometry, and the development of novel deuterated compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a critical, non-interfering reference standard for the accurate quantification of its non-deuterated counterpart or related metabolites in complex biological matrices.
• Pharmaceutical Research & Development: Used in drug discovery and development for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies to trace and quantify drug molecules.
• Metabolomics and Biomarker Discovery: Enables precise tracking and identification of metabolic pathways in biological systems, facilitating biomarker research.
• Synthesis of Deuterated Compounds: Acts as a key precursor or intermediate in the synthesis of more complex deuterium-labeled molecules for use in NMR spectroscopy and other analytical techniques.
• Agrochemical Research: Employed in environmental fate studies and residue analysis of pesticides and herbicides.
• Material Science: Investigated for potential use in the development of specialty polymers or organic electronic materials where isotopic labeling can modify physical properties.

Basic Information

Product Name	1,1-Cyclopropane-2,2,3,3-D4-Dicarboxylic Acid
CAS No.	136503-99-6
Molecular Formula	C5D4H2O4
Molecular Weight	134.12 g/mol
Synonyms	Cyclopropane-1,1-dicarboxylic-2,2,3,3-d4 Acid; 1,1-Cyclopropanedicarboxylic-2,2,3,3-d4 Acid; Deuterated Cyclopropane-1,1-dicarboxylic Acid; (2,2,3,3-D4)Cyclopropane-1,1-dicarboxylic Acid; 1,1-Cyclopropanedicarboxylic Acid-d4; Cyclopropane-1,1-dicarboxylic Acid D4; D4-CPDC
EINECS	Contact for details

Quality Control

Every batch of 1,1-Cyclopropane-2,2,3,3-D4-Dicarboxylic Acid is manufactured and analyzed under strict quality management systems to ensure the highest standards of isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including NMR and MS analysis, to confirm deuterium enrichment and chemical purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.