Description

Cyclobutene, 3,4-Dichloro-1,2-Dimethyl-, (3R-Trans)- (9Ci) is a high-purity, stereochemically defined chlorinated cyclobutene derivative. This compound serves as a valuable chiral building block and synthetic intermediate in advanced organic synthesis, offering precise structural control for complex molecule construction. It is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where its specific stereochemistry and functional groups are critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in constructing complex, stereospecific molecular frameworks.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the specific chlorinated cyclobutane structure contributes to biological activity.
• Material Science Research: Serves as a monomer or precursor for specialized polymers and advanced organic materials with unique thermal or mechanical properties.
• Organic Synthesis & Methodology: Employed in academic and industrial R&D for studying cycloaddition reactions, ring-opening transformations, and as a model substrate in catalysis studies.
• Ligand & Catalyst Development: The defined stereochemistry makes it a potential precursor for chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex fragrance, flavor, or dye molecules requiring specific stereochemistry.

Basic Information

Product Name	Cyclobutene, 3,4-Dichloro-1,2-Dimethyl-, (3R-Trans)- (9Ci)
CAS No.	136377-91-8
Molecular Formula	C6H8Cl2
Molecular Weight	151.03 g/mol
Synonyms	(3R,4R)-3,4-Dichloro-1,2-dimethylcyclobut-1-ene; trans-3,4-Dichloro-1,2-dimethylcyclobutene; 1,2-Dimethyl-3,4-dichlorocyclobutene; 3,4-Dichloro-1,2-dimethylcyclobutene (trans-); (3R-trans)-3,4-Dichloro-1,2-dimethylcyclobutene; Cyclobutene, 3,4-dichloro-1,2-dimethyl-, (3R,4R)-; 136377-91-8 (CAS)
EINECS	Contact for details

Quality Control

Our production of Cyclobutene, 3,4-Dichloro-1,2-Dimethyl-, (3R-Trans)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR to confirm identity, isomeric purity, and assay. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (Chiral HPLC)	≥ 98.0% (3R,4R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.