Description

Tiotropium Bromide is a long-acting muscarinic antagonist (LAMA) used as an active pharmaceutical ingredient (API). This compound is critical for the formulation of inhalation therapies designed to manage chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Pharmaceutical manufacturers and research institutions globally rely on high-purity Tiotropium Bromide CAS NO 136310-93-5 for developing and producing effective, long-lasting bronchodilators.

Application

• Primary Pharmaceutical API: The core active ingredient in dry powder inhalers (DPIs) and other inhalation solutions for the maintenance treatment of COPD and asthma.
• Respiratory Drug Formulation: Used in the development and commercial manufacturing of branded and generic respiratory medications.
• Clinical Research: Serves as a reference standard and key material in preclinical and clinical studies for new respiratory therapeutics.
• Drug Delivery System Development: Utilized in R&D for innovating novel pulmonary drug delivery platforms and combination therapies.
• Pharmacological Studies: Employed in academic and industrial labs to study muscarinic receptor pharmacology and airway physiology.

Basic Information

Product Name	Tiotropium Bromide
CAS No.	136310-93-5
Molecular Formula	C19H22NO4S2•Br
Molecular Weight	472.41 g/mol
Synonyms	(1α,2β,4β,5α,7β)-7-[(Hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide; Ba 679 BR; Spiriva; Tiotropium; Tiotropium Bromide Monohydrate
EINECS	Contact for details

Quality Control

Our Tiotropium Bromide is manufactured and tested under strict quality systems. We provide material that meets high-purity standards suitable for pharmaceutical applications, with comprehensive testing including identification, assay, and impurity profiling. Certificates of Analysis (COA) are available upon request, detailing compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 2.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.