Description

Ciguatoxin 4C is a potent marine neurotoxin belonging to the ciguatoxin family, identified by CAS No. 136252-00-1. This compound is of critical importance for scientific research and analytical reference in the fields of toxicology and food safety. It is primarily required by research institutions, diagnostic laboratories, and regulatory bodies for the study of ciguatera fish poisoning (CFP), method development, and the calibration of detection assays.

Application

• Analytical Reference Standard: Primary use as a certified standard for the accurate quantification of ciguatoxins in complex matrices via LC-MS/MS or other analytical techniques.
• Toxicological Research: Fundamental tool for studying the mechanism of action, potency, and metabolic pathways of ciguatoxins in biological systems.
• Diagnostic Assay Development: Critical for the development, validation, and quality control of immunoassays and cell-based assays for the detection of ciguatera toxins.
• Food Safety & Regulatory Compliance: Used by monitoring agencies and testing laboratories to screen seafood for contamination, ensuring public health safety and compliance with food regulations.
• Pharmacology Studies: Investigation of voltage-gated sodium channel modulation and the exploration of potential therapeutic antidotes for ciguatera poisoning.
• Environmental Monitoring: Reference material in studies tracking the biogeography and toxin production of Gambierdiscus and Fukuyoa dinoflagellates.

Basic Information

Item	Detail
Product Name	Ciguatoxin 4C
CAS No.	136252-00-1
Molecular Formula	C₆₀H₈₆O₁₆
Molecular Weight	1063.3 g/mol
Synonyms	CTX4C; Ciguatoxin-4C; C-CTX-1; 54-deoxy-50,51-didehydro-49,52,53-trinor-2,3-dihydroxyCTX3C; Pacific Ciguatoxin-1; P-CTX-1 (Note: Often used interchangeably for the main Pacific congener); (2S,4R,6R,7R,8R,14R,15R,16R,18S,19R,20R,21S,24S,25S,26R,28S,30S,32S,34S,35R,36R,37S,38R,39S,40R,41S,43R,44R,45S,46R,48S,49S,50S,52S,53S,54S,55S,56S,57S,58S,59S,60S)-2,4,6,7,8,14,15,16,18,19,20,21,24,25,26,28,30,32,34,35,36,37,38,39,40,41,43,44,45,46,48,49,50,52,53,54,55,56,57,58,59,60-tetratetracontahydroxy-3,5,9,13,17,22,27,31,33,42,47,51-hexamethyl-10,12,23,29-tetraoxaheptacyclo[27.25.0.0¹⁴,¹⁸.0²⁰,²⁴.0²⁶,³⁰.0³²,⁴⁶.0³⁴,⁴⁴]hexacontane-11,60-dione (IUPAC)
EINECS	Contact for details

Quality Control

Our Ciguatoxin 4C is produced and handled under strict quality protocols to ensure the highest purity and stability for critical research applications. Each batch is characterized using advanced analytical techniques including NMR and high-resolution mass spectrometry for structural confirmation, with purity verified by HPLC. A comprehensive Certificate of Analysis (COA) detailing batch-specific data, including purity, identity, and chromatographic profile, is provided to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with reference
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.